Donor Drug Overdose Not Associated with Primary Graft Dysfunction after Heart Transplantation
نویسندگان
چکیده
منابع مشابه
Primary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
متن کاملPrimary Graft Failure after Heart Transplantation
Primary graft failure (PGF) is a devastating complication that occurs in the immediate postoperative period following heart transplantation. It manifests as severe ventricular dysfunction of the donor graft and carries significant mortality and morbidity. In the last decade, advances in pharmacological treatment and mechanical circulatory support have improved the outlook for heart transplant r...
متن کاملReceptor for advanced glycation end products in donor lungs is associated with primary graft dysfunction after lung transplantation.
Development of primary graft dysfunction (PGD) is associated with poor outcomes after transplantation. We hypothesized that Receptor for Advanced Glycation End-products (RAGE) levels in donor lungs is associated with the development of PGD. Furthermore, we hypothesized that RAGE levels would be increased with PGD in recipients after transplantation. We measured RAGE in bronchoalveolar lavage fl...
متن کاملExpression profiling of human donor lungs to understand primary graft dysfunction after lung transplantation.
Lung transplantation is the treatment of choice for end-stage pulmonary diseases. A limited donor supply has resulted in 4,000 patients on the waiting list. Currently, 10-20% of donor organs offered for transplantation are deemed suitable under the selection criteria, of which 15-25% fail due to primary graft dysfunction (PGD). This has spawned efforts to re-examine the current selection criter...
متن کاملPercutaneous Extracorporeal Membrane Oxygenation for Graft Dysfunction after Heart Transplantation
BACKGROUND We evaluated the safety and efficacy of percutaneous extracorporeal membrane oxygenation (ECMO) in patients with primary graft dysfunction after heart transplantation. METHODS Of 65 patients (44 males and 21 females) who underwent heart transplantation from January 2006 to December 2012, 13 patients (group I) needed peripheral ECMO support due to difficulty in weaning from cardiopu...
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ژورنال
عنوان ژورنال: The Journal of Heart and Lung Transplantation
سال: 2021
ISSN: 1053-2498
DOI: 10.1016/j.healun.2021.01.813